Major breakthrough as pig-to-human kidney transplant succeeds for a month@eriknjoka brings you this report
— WION (@WIONews) August 16, 2023
With only a single genetic modification—and no experimental medications or devices—a pig kidney xenotransplantation at NYU Langone Health led by Dr. Robert Montgomery continues to function optimally after 32 days.
— NYU Grossman School of Medicine (@nyugrossman) August 16, 2023
This is some kind of sick sorcery.
Blood banks were bad enough, but pig organs in humans are beyond the pale.
Wouldn’t you rather just die than become part pig?
Why is everyone so afraid of death?
In a medical breakthrough, NYU Langone Health surgeons successfully transplanted a pig kidney into a brain-dead man, who has now survived on the organ for more than a month.
“This represents the longest period that a gene-edited pig kidney has functioned in a human, and the latest step toward the advent of an alternate, sustainable supply of organs for transplant,” according to an NYU Langone Health news release.
The surgical staff also gave a special thanks to Mary Miller Duffy, the sister of the brain-dead man, Maurice Miller, who allowed her brother’s body to be used for the innovative procedure.
Research on the first-of-its-kind operation, which took place July 14, will continue into mid-September, as doctors monitor how long the animal’s kidney will function properly inside a human body beyond 32 days.
The pig kidney had only “one genetic modification and [is] without experimental medications or devices,” according to Montgomery.
In xenotransplants, the medical term for a cross-species organ transplant, Montgomery and his team had to create a unique solution for the patient’s body to avoid “hyperacute rejection” of the animal’s organ once it connected to the 57-year-old man’s circulatory system.
This was done by “knocking out” the alpha-gal gene that doctors altered to prevent a rejection in the man.
Additionally, the pig’s thymus gland — which communicates with its immune system — “was embedded underneath the outer layer of the kidney to stave off novel, delayed immune responses.”
“The combination of modifications has been shown to prevent rejection of the organ while preserving kidney function,” according to NYU.
This potentially game-changing surgery, part of a larger study on the subject, could someday prove an efficient treatment for the more than 103,000 people in need of organ transplants across the US.
“There are simply not enough organs available for everyone who needs one,” said Montgomery, who himself had a heart transplant five years ago. “Too many people are dying because of the lack of available organs, and I strongly believe xenotransplantation is a viable way to change that.”
They’re not putting any pig organs in me, I can tell you that much.